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A Repeated Measures ANOVA model was used for evaluating changes in health effects indicators at different time points (4 time points: baseline, F/up 1, F/up 2, and F/up 3): health effects indicators were entered into the model as within factor for assessing changes with time, while the study group (EC users/Controls) was entered as between factor for evaluating its effect on possible changes

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Gower A, Evennett N, Beban G, Yi E, Chen E