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We chose the async review, but a follow-up message told us a video call was required, so we scheduled a 15-minute appointment for the next available slot two days out

doi: 10.21037/atm-21-6942 91 BezerraFSLanzettiMNesiRTNagatoACSilvaCPEKennedy-FeitosaEet al

401 Surgical transgastric debridement with internal drainage offers more efficient necrotic tissue clearance than endoscopic approaches do, likely because of the creation of a larger cystogastrostomy opening

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These changes lead to an overall increased permeability of the BBB and imbalance of the CNS microenvironment, as well as the potential introduction of pathogens and neurotoxins into the brain that can contribute to neurodegenerative processes (Funk et al., 2021