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Another study reported both coenzyme Q 10 and vitamin E deficiencies among FRDA patients and suggested that co-supplementation with both compounds, at doses as low as 30 mg/day of coenzyme Q 10 and 4 IU/day of vitamin E, might improve disease symptoms (80)

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[124] As of 2025, the Global Fortification Data Exchange reports that folate is a mandatory fortified vitamin in 70 countries, exceeded only by iodine in 126 countries and iron in 87

controlling OS either by using antioxidants [15], [16] or by overexpressing antioxidant enzymes [17], [18] restores beta-cell function