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In boys, germ cells continue to develop until puberty, and this is a vulnerable period when exposure to tobacco smoke can affect the cells and cause epigenetic changes, Bui said.

- 8M deaths per year 100M deaths over 20th century estimates as high as 1 billion deaths this century Short thread from our @OurWorldInData entry on Smoking: ourworldindata.org/grapher/number 1/ Tobacco is the cause of 8 million premature deaths each year 7M from smokers 1.2M from secondhand smoke For reference: 1.2M people die in road accidents each year [although a younger demographic]

Journal of Allergy and Clinical Immunology: Global , 2026

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