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In addition, TACE/TGF-/EGFR signaling pathway is found activated in CSE-exposed human airway epithelial cells, and blocking the TACE/TGF-/EGFR signaling pathway can inhibit the CSE-induced EMT process [138]
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Moreover, microbiome-targeted therapies, including the use of antimicrobial peptides or specific bacteriophages, may provide more direct means of modulating microbial communities to reduce disease risk
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