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However, depending on the inherited genetics of the mouse, the particular driver mutation that was acquired altered the activity of other cancer-associated signalling pathways, as well as causing a striking tendency for whole-genome duplication, an event in which the entire set of chromosomes is doubled

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In this study, we found a significant difference between subjects smoking more than 20 cigarettes/day and those smoking less than 20 cigarettes/day ( 2 = 22.4