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His surviving family members said that they are determined to honor his legacy by living up to his indefatigable work ethic and continuing to grow their firm within a fast-changing industry

This work was supported by the National Institutes of Health/National Cancer Institute (NIH/NCI) [P01CA138338]

Secondary source studies such as systematic reviews, meta-analyses, literature reviews, and narrative reviews were excluded, as were letters to the editor, comments, special articles, and editorials

Without tobacco, ZYN reduces user exposure to tobacco-specific nitrosamines (TSNAs) and polycyclic aromatic hydrocarbons

A survey from BMJ journals found that of the smoking population, nearly half smoked over 20 cigarettes per day