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Our findings reveal that tirzepatide attenuates alcohol-induced dopamine signalling, reduces alcohol consumption, and suppresses relapse-like behaviours. Because alcohol, nicotine, and many drugs of abuse hijack the brains reward circuitry, dampening dopamine spikes could help explain why alcohol seemed less compelling to the animals

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The weight trajectories of individuals are graphed in Figure 2B

These can include pancreatitis, which is when the pancreas becomes inflamed