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PMID 12090453

Role of Nicotine in Delayed Wound Healing Nicotine, a highly addictive compound found in s, can negatively affect wound healing

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the cells become swollen and inflamed Promotes the buildup of plaque (fat, cholesterol, calcium and other substances) in blood vessels and even plaque rupture (resulting in an heart attack) A recent study found smoking is also associated with a thickening of the heart and lowers the heart's pumping abilityboth of which are associated with heart failure

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