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Price increases have been shown to have the largest impact on youth initiation into tobacco use and quitting, Koenemann has said

The HDL-Atherosclerosis Treatment Study (HATS), a three-year randomized controlled trial in 160 patients with documented CHD and low HDL concentrations, found that a combination of simvastatin and nicotinic acid (2-3 g/day) increased HDL concentrations, inhibited the progression of coronary artery stenosis (narrowing), and decreased the frequency of cardiovascular events, including myocardial infarction and stroke, compared to placebo (88)

Many effects only become visible after prolonged use, making counterfeit cigarettes especially dangerous

But he and others argue that a better approach would be legislation that considers a molecules chemical structure and function

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