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The measurement of TCN2-Cbl provides a more accurate reflection of the vitamin B12 status, particularly in the context of neurological disorders, as it specifically quantifies the fraction of Cbl bound to TCII and available for cellular uptake and metabolism [133]

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JPT's peptide stability guidance makes the same broad distinction: lyophilized peptides can remain stable for months to years when stored properly, while reconstituted materials require tighter handling