Redox Biol 42:101887 Marrocco I, Altieri F, Peluso I (2017) Measurement and clinical significance of biomarkers of oxidative stress in humans
While more human trials are needed to further explore this topic, one study showed depleted levels of glutathione in the hippocampus of generally healthy elderly persons, resulting in mild cognitive impairment, a precursor to more advanced impairment down the road
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There was no significant difference between the glutathione supplement and placebo groups in terms of subjective efficacy
2 Department of Biological Science, Purdue University, West Lafayette, IN, USA *These authors contributed equally to this work Abstract: Glutathione S-transferase (GST) is a Phase II metabolic enzyme that is an important facilitator of cellular detoxification