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Mechanistic studies further revealed that miR-130b-MV upregulated the mRNA expression of key lipolytic enzymes, including HSL and MGLL, while exerting no significant impact on the mRNA levels of FASN and ACC

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By thoroughly investigating the systemic effects mediated by the carnitine pool, including its impacts on the liver, gut, kidney, muscle, heart, lung, and eye, we emphasize the importance of maintaining carnitine pool homeostasis for overall metabolic health and inter-organ metabolic cooperation