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Cortijo et al., The Relaxant and Spasmogenic Effects of Some Xanthine Derivatives Acting on Guinea-pig Isolated Trachealis Muscle, British Journal of Pharmacology, August 1988;94(4):10911100

If you are trained in its use, follow the instructions provided

During smoking, this complex biomass is subjected to high temperatures and varying oxygen concentrations, producing an incomplete combustion that generates more than 7,000 toxic compounds

The smokeless tobacco consumers had significantly elevated levels of epinephrine in comparison with the non-consumers (Figure 1)