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The evidence is sufficient to infer a causal relationship between secondhand smoke exposure from parental smoking and lower respiratory illnesses in infants and children

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For women, those who smoked one cigarette per day had 31 per cent of the excess risk of heart disease and 34 per cent of the excess risk of stroke associated with smoking 20 cigarettes per day

Also, we found that nicotine promotes cell migration of VSMCs GbaSM-4 cells isolated from basilar arteries of guinea pigs, and this cell migration is inhibited by methyllycaconitine, an antagonist of nAChRs [27]