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1 However, NSAIDs should be used with caution if youre already experiencing stomach symptoms, and opioid-based painkillers should be used with awareness of the additive constipation risk

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Subsequent and larger datasets suggest the relative risk may be smaller than this early estimate, especially when compared against agents such as empagliflozin or sitagliptin

No matter what option you choose, you should explore these options with healthcare providers: this is essential to determine the most effective course of action