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Figure 3 Survival through winter occurs best where there are warm soil microclimates, such as those found around the foundations of heated buildings

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Experimental Considerations Given the duration of the intervention (8 mo) and the intensive protocol of smoke exposure (2.5 h 5 days/wk), the SMO group was limited to 10 mice, which is within the range for studies investigating long-duration exposure to smoke (25, 27, 57)

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