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Hematologic and biochemical monitoring throughout the trials revealed no concerning patterns in blood counts, liver function tests, kidney function markers, or other laboratory parameters

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FIGURE 3 The PPI-mediated alteration of bacterial metabolites, such as SCFAs, lactic acid and histamine, is a crucial mechanism in the development of certain digestive complications

Finally, we highlighted the moments where the moving average and numerical derivative were both greater than 0.6 (Supplementary Figures S6876)