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Similarly, patients with conflicting data on the key criteria of fatigue, unrefreshing sleep, and postexertional malaise, who could not be dependably identified from documentation thereafter, were excluded (13, 17, and 55 patients, respectively)

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Birtic S, Dussort P, Pierre FX, Bily AC, Roller M

A redox-active cofactor for several biosynthetic enzymes, also functioning as an RTA by reacting with peroxyl radicals, yielding oxidation products such as dihydrobiopterin (BH 2 ), which can be reduced back to BH 4 by the enzyme dihydrofolate reductase

Wang HH, Fan SQ, Zhan YT, Peng SP, Wang WY