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Drugs that work through the GST system include GST inhibitors and their respective prodrugs

Its induction exerts direct tumor-suppressive effects through iron-mediated oxidative damage, yet paradoxically drives pro-tumorigenic adaptations in the tumor microenvironment (TME), particularly in advanced PCa with dysregulated iron metabolism [66,67]

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In the BioFINDER cohort study, CSF ferritin levels reaching a threshold value of 12.47 ng/ml predicted cognitive deterioration in patients with mild cognitive impairment (81)