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Description

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ROS activates p38 and c-Jun N-terminal kinase (JNK), and subsequently interferes with insulin signaling by increasing serine phosphorylation of insulin receptor substrate 1 (IRS-1) at specific sites, ultimately leading to insulin resistance

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Protein expression of hypothalamic GHSR, SST, and pituitary SSTR-2 and -5 showed the same patterns as those for mRNA expression (Fig

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& Ilan, Y

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This means it stays active longer and is easier for the body to use

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