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Nonetheless, the mechanistic complementarityspanning vascular delivery, metabolic signaling, and mitochondrial efficiencyoffers a biologically plausible rationale for further investigation, particularly in early disease stages where restoring energy balance may yield the greatest protective effect

Zepbound may cause slightly more diarrhea compared to Wegovy, particularly in the early dose stages

2015 Apr;25(2):59-65

Its absorbed in the small intestine and quickly excreted, so it doesnt spike your blood sugar, making it an attractive alternative for people with diabetes

For patients who need to lose 20-30% of their weight, Im honest that diet and exercise are essential for health, but alone they rarely achieve that level of weight loss