melanotic macule pathology macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight ⬆️ in single basal melanocytes; NO nests. More info like this in Melanotic Macules, Naevi, and Melanoma

melanotic macule pathology

melanotic macule pathology macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight ⬆️ in single basal melanocytes; NO nests. More info like this in Melanotic Macules, Naevi, and Melanoma

Name: melanotic macule pathology macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight ⬆️ in single basal melanocytes; NO nests. More info like this in Melanotic Macules, Naevi, and Melanoma
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Ipamorelin stimulates growth hormone release by targeting ghrelin receptors, allowing for growth hormone release with minimal impact on other hormones

Thus, ROS production, caused by AFs, drives immune cells to prooxidant/inflammation status, such as autophagy and extracellular trap formation in macrophages, through TLRs (59)