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It has been extensively characterised in preclinical in-vitro and in-vivo models for its cytoprotective, angiogenic, and anti-inflammatory properties across a range of tissue types

VEGF initiates the formation of new blood vessels to supply the growing repair tissue

Additionally, as mentioned above, ECT elicits an immune response and, due to destroyed blood vessels, helps prevent bleeding of the lesion following the treatment

[DOI] [PMC free article] [PubMed] [Google Scholar] 72.Braniste V., Leveque M., Buisson-Brenac C., Bueno L., Fioramonti J., Houdeau E