can tirzepatide make you depressed and Depression Risk | Mental Health Guide Mental Health Effects of Tirzepatide:

The request applies to Novo Nordisks Wegovy and its older drug Saxenda, as well as Eli Lillys Zepbound

Direct Effects on the Optic Nerve: Some research suggests that GLP-1 receptors are present in the optic nerve, raising the possibility that these drugs may directly affect neural tissue in ways that increase vulnerability to ischemia

Syncing GLP-1 Timing With Your Clinical Genetics Your genetic makeup influences how quickly your body responds to GLP-1 signaling, which means the 'optimal' timing for one person may differ slightly from another based on variants in genes like GLP1R (rs6923761) and GIPR (rs1800437)

Yes, studies suggest it is safe for long-term use, but ongoing monitoring is recommended

(236) in a study of 246 children observed that magnesium intake was inversely associated with asthma and atopic sensitisation