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Tufts Now: Dariush Mozaffarian : GLP-1s have captured national attention for their ability to help people achieve significant weight reduction, but successful weight loss requires more than a prescription
Above, we summarized the peptides research-backed benefits and side effects, and illuminated worthwhile directions for future research
The affected medications include: Semaglutide (Ozempic, Rybelsus, Wegovy) Liraglutide (Saxenda, Victoza) Tirzepatide (Mounjaro, Zepbound) New Warning Details The updated label now includes a subsection under "Warnings and Precautions" that states: "There have been rare postmarketing reports of pulmonary aspiration in patients receiving GLP-1 receptor agonists undergoing elective surgeries or procedures requiring general anesthesia or deep sedation who had residual gastric contents despite reported adherence to preoperative fasting recommendations." This warning highlights the potential risk of stomach contents entering the lungs during surgical procedures, even when patients have followed fasting guidelines
Advanced glycation end products (AGEs) accumulate with age, diabetes, and renal failure, promoting vascular inflammation through the AGE-RAGE axis