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In the SUSTAIN clinical trial program evaluating Ozempic for type 2 diabetes, injection site reactions were reported in 1.2-1.4% of patients receiving semaglutide compared to 0.7% receiving placebo

[DOI] [PMC free article] [PubMed] [Google Scholar] 29.Monami M, Dicembrini I, Nardini C, Fiordelli I, Mannucci E

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TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species

Specific activities have previously been reported for commercial enzyme preparations of GST M1-1 (3.7 mol min 1 mg 1 ), GST A1-1 (14.9 mol min 1 mg 1 ), and GST P1-1 (0.15 mol min 1 mg 1 ) at pH 6.5 and 25 C 8 , but later redetermined with somewhat altered conditions of pH 7.4 and 37 C to the higher values of 66.3, 126, and 1.36 mol min 1 mg 1 , respectively 17 The latter values are in general agreement with the values in Table 1 considering differences in reaction temperature and other conditions