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Hyperuricemia may be an independent and possibly causal risk factor for such diseases due to reported effects of soluble urate on vascular cells and possibly indirect effects of gouty inflammation

10.1016/j.neuint.2017.07.001 50 LscherW.HnackD.FassbenderC

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Water retention : Possible with sustained use, related to GH-mediated effects rather than the peptide itself

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