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The ability to try a wide range of flavours and nicotine levels is also appealing, and liquids tend to be cheaper than e-cigarettes, widening the price gap with traditional cigarettes

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TSPO radioligand binding correlates with the presence of activated microglia identified by immunohistochemistry in situ [12] and immunohistochemistry combined with autoradiography in brain tissue [9, 13], and is elevated in illnesses known to be associated with gliosis [14], though TSPO signal also arises from astroglia and endothelial cells [15]