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The HGF/c-Met pathway plays a key role in the progression of metastasis by influencing cell-cell junctions, supporting cytoskeletal remodeling, and controlling integrin function, among other functions [18]

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In vivo pharmacology Female db/+ mice received a single intravenous dose of ReninAAV (1.510 10 GC) by study week -5 and underwent unilateral nephrectomy (UNx) at study week -4, resulting in diabetic nephropathy hypertensive mice (DN/HT) (stergaard et al., 2021b

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