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DDx: Malignant melanoma - often lacks a Grenz zone (lesion in papillary dermis), [22] mitotic figures, necrosis, cytologic atypia, asymmetry (architecture, pigment)

There is a strong interest in developing obesity treatments based on glucagon-like peptide-1 (GLP-1) agonists, which have proved to limit morbidity and mortality in type 2 diabetes

These range from FDA-approved medications, such as GLP-1 receptor agonists (Wegovy, Zepbound) for weight loss, to unregulated compounds with minimal or no human safety data

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