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1999: RJRs sale to the Japanese | The food and tobacco empire of RJR Nabisco broke apart when the company sold its international tobacco business to Japan Tobacco for $7.8 billion

While some may remain skeptical about its effectiveness, anecdotal evidence suggests that it can help a lot of people quit smoking or manage other addictions and psychological problems

The authors also noted that some documents contained limited country-level detail for certain regions

Executives said they had no knowledge of how the Food and Drug Administration viewed the deal

Less than half (43 per cent) of those affected survive five or more years