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MVMR analysis revealed that, after adjusting for BMI and T2DM, genetically proxied GLP-1RAs did not have a significant effect on the risk of AF (OR = 1.06, 95% CI = 0.601.89, p = 0.848) or cardiac arrest and ventricular fibrillation (OR = 1.28, 95% CI = 0.364.52, p = 0.705) (Supplementary Table S4)