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For a patient on the standard titration, this single vial can cover the entire ramp from 2.5mg through 15mg weekly doses, with enough volume for multiple weeks at each tier

Glover TW, Stein CK, Legius E, Andersen LB, Brereton A, Johnson S

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166 Moreover, this implies that tirzepatide more strongly affects the absorption of oral contraceptives and that this increased impact may be driven by rapid dose escalation