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Biological pathogenesis of chronic fatigue The exact pathogenesis of CFS remains elusive, however several mechanisms have been implicated in the alteration of immune function, hormonal regulation, metabolic changes, and host response to oxidative stress

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Detailed projections of the current and future revenues from the sales of drugs developed by the leading players, namely Boehringer Ingelheim, Eli Lilly, Novo Nordisk and other players

Further, it revealed that PI3k inhibitors blocked the enhanced post-synaptic transmission, suggesting this effect might be dependent on PI3k activation [13]