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When evaluated after exposure to LASSS at a 1:8000 molar ratio to HGF and subsequent ultra-filtration to wash-out un-reacted free LASSS, c-met binding affinity increased more than two-fold over the original non-nitrated HGF

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The penicillin thioester, previously identified by 1 H-NMR, is the first detectable product in the reaction, which subsequently undergoes hydrolysis to the benzylpenicilloic acid ( Figure 3B ) (Llinas et al., 2000)

10.1038/s41598-021-81815-2 108 WangZ.KwanM

**Other Indications:** May be used as part of a treatment regimen for certain metabolic disorders or conditions that require vitamin B12 supplementation