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J., Daugherty, S

NICE specifically advises against initiating the following medications for chronic primary pain (including fibromyalgia): antiepileptics (including gabapentinoids such as pregabalin and gabapentin), opioids, paracetamol, non-steroidal anti-inflammatory drugs (NSAIDs), benzodiazepines, corticosteroids, and antipsychotics

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A primary potential application for these vesicles is their hollow aqueous core, which can carry and distribute Dox by encapsulation, achieving a drug loading capacity of 7.8% with a drug-to-vesicles mass ratio of 1:10