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Pharmacokinetics and brain distribution of the therapeutic peptide liraglutide by a novel LCMS/MS analysis

The bioactive natural product T1 , bis(4-hydroxybenzyl)sulfide, with the most striking inhibitory potency against tyrosinase, was chosen as the target compound to characterize its biological effects in tyrosinase inhibition, cell viability, in vitro and in vivo melanin biosynthesis and acute oral toxicity in mice

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But there is still little clinical research in dogs, and the use in a veterinary practice is still regarded as an investigational/off-label use

Peer review Peer review information Nature Reviews Endocrinology thanks Jonathan Campbell and the other, anonymous, reviewer(s) for their contribution to the peer review of this work