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That changes how patients handle fasting, react to stress and recover from tissue insult

Dolianitis C, Kelly J, Wolfe R, Simpson P

Pineal peptides work best as part of a comprehensive sleep optimization strategy that includes appropriate light exposure (bright in morning, dim in evening), consistent sleep-wake times, cool sleeping environment (65 to 68 degrees Fahrenheit), limited stimulants after noon, and reduced screen exposure before bed

These effects appear to increase with the duration of treatment

The lack of VO2max improvement despite weight loss is concerning for endurance athletes whose performance depends heavily on cardiorespiratory fitness