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To rigorously compare the effects of CDK11 inhibition and SNIP1 loss on splicing we compared fold changes of intron ratios between OTS964- and DMSO-treated HCT116 cells from our previous study 8 and between dTAG-induced SNIP1 depletion and DMSO control in dTAG SNIP1 HCT116 cells across 12727 protein-coding genes

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The medication carries a boxed warning regarding thyroid C-cell tumors observed in rodent studies, though human relevance remains uncertain

After propensity score matching, there were 336,655 in each cohort

Effects of PPM1K rs1440581 and rs7678928 on serum branched-chain amino acid levels and risk of cardiovascular disease