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For patients with type 2 diabetes, either medication addresses both blood sugar management and weight, which is particularly relevant for the over-50 population where type 2 diabetes prevalence is significantly higher

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Compound 6 is at least 25 times more potent against TGR than human TrxR1 indicating that selective enzyme inhibition is possible

[5] reported a survival difference between the subtypes, even in a total MPNST group (including localized and metastatic disease) and attributed this difference to the more frequent incidence of metastatic disease among patients with NF-1