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A recent report showed that HK-2-mediated H3K18la enrichment at the promoter of the Acta2 gene in TGF-1-induced hepatic stellate cells (HSCs) was a prerequisite for HSC activation and liver fibrosis [29]

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Across studies, reported weight loss generally ranged from approximately 4% to more than 11% of TBW over follow-up periods spanning 3 to 15 months, with some reporting that 58% to 67% of patients achieved at least 5% TBW loss

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