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Company executives frame the partnership as both a commercial and healthcare access initiative

10.3892/or.2015.3805 25 ChenG.XuS.RenkoK.DerwahlM

The powder will dissolve completely into a clear solution within a minute or two

In contrast and although LnCaP, a prostate cancer line, proved to be particularly sensitive to metformin and in a concentration range that was within that expected clinically and correlated with a high expression of mRNA for OCT3 and low expression of MATE2 for the other cell lines, very high concentrations, up to 10mM, of metformin were required to see significant inhibition, and a strong significant correlation between inhibition of proliferation and MATE2 expression was not seen (254)

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