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In 48 adults with alcohol use disorder, semaglutide significantly reduced alcohol self-administration and weekly craving, with effect sizes exceeding those historically seen with naltrexone or acamprosate

On the other hand, primary hepatic cells exposed to CCl4 (4 mM) presented a significant reduction in cell viability when compared to the control group

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Combined with biomarkers like fasting glucose, insulin, and lipids, this information should be interpreted with a qualified healthcare provider to inform personalized therapy discussions