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PMID: Summary Keywords biologic therapy, early psoriatic arthritis, GLP-1 receptor agonists, inflammation, metabolic syndrome, psoriasis Citation Ciancio G, Maranini B, Sandri G, Amati G, Bortoluzzi A, Silvagni E, Govoni M and Giuggioli D (2026) Glucagon-like peptide-1 receptor agonists in psoriasis and psoriatic arthritis: emerging evidence and future research opportunities

The FDA-approved prescribing information for Mounjaro (tirzepatide for diabetes) does not list anger or irritability as recognized adverse effects

Seixas E, Ferreira PG

For example, theres emerging evidence that these medications may help with conditions like inflammatory bowel diseases such as Crohns disease and ulcerative colitis

* CJC-1295 works on the pituitary