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An obvious decrease of up to 59% of relative total trabecular density was recorded compared to normal control samples with a significant decrease of the trabecular thickness, and a significant loss of osteoblastic activity was shown with focal records of trabecular cracks and fissures with a marked increase of intertrabecular marrow spaces accompanied by remarkable hypoplasia of bone marrow with significant vacuolization recorded

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Int J Mol Sci 21(24):9710 Page MJ et al (2021) PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews

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