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It has been speculated that when peroxide activates ATM in vitro little autophosphorylation takes place and it may be partially dependent on complexing with the MRN complex recruited to DNA repair 51,76

2016 Aug;33(8):2033-42

the label's animal-derived estimate is an intravenous dose up to 30 mL in an adult without toxic effects, and a peptide vial uses only a few mL

So at the mechanistic level: BPC-157 builds the blood supply

This major limitation is the current research focus of multiple research groups, aiming at new co-culture models (e.g., assembloids and OoC models) to improve the mimicry of the endometrium