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In healthy volunteers, two biomarkers for heightened vascular risk, microvesicles, and endothelial progenitor cells, were increased following exposure to e-cigarettes (180), and these effects were shown to be dependent on nicotine (181)

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In general, the differences between a smokers lungs and healthy lungs include the following: Increased mucus production Smoking may cause the lungs to This increased mucus production can happen for a few reasons, but it primarily occurs because smoking cigarettes damages the epithelial cells that line the airway

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Bulow J, Klemperer P