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Trypsin/P was set as the enzyme parameter, a maximum of 2 missed cleavage was allowed, carbamidomethylation was set as a fixed modification and methionine N-terminal excision and oxidation were set as variable modifications with a maximum of 2 allowed per peptide

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Bowers K, Li Q, Bressler J, Avramopoulos D, Newschaffer C, Fallin MD (2011) Glutathione pathway gene variation and risk of autism spectrum disorders