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"She'll be the dragon lady," said Les, "Cruella de Vil, and make everyone else uncomfortable and funny." The fit was initially awkward, which forced the writers to avoid the issue altogether

Isabel Allende, Writer : It was a time when the best and the worst of people was on the surface

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Further studies showed that miRNA-218-5p directly targeted bromodomain containing 4 (BRD4), and overexpression of miRNA-218-5p reversed cell apoptosis by regulating BRD4

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